Abstract #2054

Fast T1rho mapping in mice using an optimized Bloch simulation based radial sampling pattern

Maximilian Gram^1,2, Daniel Gensler^1,3, Patrick Winter^1,2, Michael Seethaler^2,3, Peter Nordbeck^1,3, and Peter Jakob²

¹Department of Internal Medicine I, University Hospital Würzburg, Würzburg, Germany, ²Experimental Physics 5, University of Würzburg, Würzburg, Germany, ³Comprehensive Heart Failure Center (CHFC), University Hospital Würzburg, Würzburg, Germany

Myocardial T_1ρ-mapping in small animal studies is still a challenging procedure. Commonly, T_1ρ-mapping requires long measurement times or only provides insufficient image quality due to a low signal-to-noise-ratio. Using a novel approach based on an optimized radial sampling pattern and high flip angles, we were able to overcome both restrictions. By a special sorting of golden angles based on Bloch simulations the image quality of the method could be significantly increased, and a high quantification accuracy could be realized. Thus, the new approach is a reliable method for fast T_1ρ-mapping in future studies on small animals.

How to access this content:

For one year after publication, abstracts and videos are only open to registrants of this annual meeting. Registrants should use their existing login information. Non-registrant access can be purchased via the ISMRM E-Library.

After one year, current ISMRM & ISMRT members get free access to both the abstracts and videos. Non-members and non-registrants must purchase access via the ISMRM E-Library.

After two years, the meeting proceedings (abstracts) are opened to the public and require no login information. Videos remain behind password for access by members, registrants and E-Library customers.

Click here for more information on becoming a member.