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Abstract #2054

Fast T1rho mapping in mice using an optimized Bloch simulation based radial sampling pattern

Maximilian Gram1,2, Daniel Gensler1,3, Patrick Winter1,2, Michael Seethaler2,3, Peter Nordbeck1,3, and Peter Jakob2
1Department of Internal Medicine I, University Hospital Würzburg, Würzburg, Germany, 2Experimental Physics 5, University of Würzburg, Würzburg, Germany, 3Comprehensive Heart Failure Center (CHFC), University Hospital Würzburg, Würzburg, Germany

Myocardial T-mapping in small animal studies is still a challenging procedure. Commonly, T-mapping requires long measurement times or only provides insufficient image quality due to a low signal-to-noise-ratio. Using a novel approach based on an optimized radial sampling pattern and high flip angles, we were able to overcome both restrictions. By a special sorting of golden angles based on Bloch simulations the image quality of the method could be significantly increased, and a high quantification accuracy could be realized. Thus, the new approach is a reliable method for fast T-mapping in future studies on small animals.

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