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Abstract #2064

Dynamic changes of tissue characteristics by T1 and T2 mapping in patients with peripartum cardiomyopathy

Yaodan Liang1, Yuanwei Xu2, Weihao Li2, Jing An3, and Yucheng Chen2
1Department of Cardiology, Beijing Hospital, Beijing, China, 2Department of Cardiology, West China Hospital, Chengdu, China, 3Siemens Shenzhen Magnetic Resonance Ltd, Shenzhen, China

This study aimed to demonstrate the dynamic changes of tissue characteristics in patients with peripartum cardiomyopathy (PPCM). Cardiovascular magnetic resonance (CMR) examination was performed using a 3.0T MR scanner, consisted of a MOLLI sequence for T1 mapping, and a T2 prep with bSSFP for T2 mapping. Ten PPCM patients with repeated CMR and 20 healthy age-matched females were analyzed. After a median 15.3-month follow-up, five patients had a recovered left ventricular ejection fraction. PPCM patients showed significantly higher native T1, extracellular volume, and T2 than normal controls. Furthermore, native T1 decreases significantly in the follow-up CMR of PPCM patients.

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