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Abstract #2079

Extra-cellular volume (ECV) mapping using fast single-breathhold 2D multi-slice myocardial T1 mapping (FAST1) at 1.5T

Li Huang1, Radhouene Neji1,2, Filippo Bosio1, Amedeo Chiribiri1, Reza Razavi1, and S├ębastien Roujol1
1School of Biomedical Engineering and Imaging Sciences, Faculty of Life Sciences and Medicine, King's College London, London, United Kingdom, 2MR Research Collaborations, Siemens Healthcare Limited, Frimley, United Kingdom

Extra-cellular volume (ECV) mapping using combined native and post-contrast myocardial T1 maps shows promise in assessing cardiomyopathies. However, its feasibility for full left ventricular (LV) coverage is limited using conventional myocardial T1 mapping techniques such as modified Look-Locker inversion recovery (MOLLI) with single-slice acquisition per breathhold. The previously proposed fast single-breathhold 2D multi-slice myocardial T1 mapping (FAST1) technique can provide time-efficient full LV coverage. In this work, its capability for ECV mapping with full LV coverage at 1.5T is evaluated. Compared to MOLLI, FAST1 yields 4-fold increased spatial coverage, limited penalty of ECV spatial variability and highly correlated ECV values.

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