.The purpose of our study was to evaluate T1-mapping for the comparison of chronic myocarditis, nonischemic dilated cardiomyopathy (DCM) and hypertensive heart disease using two MOLLI schemes in a clinical setting. We prospectively enrolled 81 patients investigated for suspected myocarditis that underwent a cardiac magnetic resonance protocol including consecutively acquired 3(3)3(3)5MOLLI and 5(3)3 MOLLI T1-mapping. We performed an overall and segmental analysis on a single mid ventricular short-axis slice. The results from the two MOLLI schemes are very similar. A segmental evaluation of 5(3)3MOLLI data could enable refining diagnosis in clinical practice, particularly when DCM is within the differential diagnoses.