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Abstract #2084

A novel generalized modeling of modified Look-Locker inversion recovery (MOLLI) signal to allow a shorter breath-hold and accurate T1 mapping

Seonghwan Yee1 and Seonghwan Yee2
1CU Anschutz medical, Aurora, CO, United States, 2Radiology, University of Colorado Anschutz Medical Campus, Aurora, CO, United States

A novel generalized modeling method is presented here for the MOLLI signal. When compared with the conventional 3-parameter exponential modeling, this new modeling demonstrates the better accuracy, particularly with the larger T1 values in the case of using enhanced acquisition timing scheme (e.g. 4s(1s)3s(1s)2s). The fact that this novel modeling method does not require full recovery of longitudinal magnetization in successive inversion pulses strongly suggests the possibility of further reducing the total MOLLI scan time to the level a few seconds less than 10 s, which would be much beneficial for those patients who have difficulty in holding the breath.

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