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Abstract #2085

Detection of myocardial change in primary aldosteronism and essential hypertension with T1 mapping

Tao Wu1, Yan Ren2, Wei Cheng1, Wei Wang2, Fangli Zhou2, Xiaoyue Zhou3, Yucheng Chen4, and Jiayu Sun1
1Department of Radiology, West China Hospital, Chengdu, China, 2Department of Endocrinology and Metabolism, Adrenal Center, West China Hospital, Chengdu, China, 3MR Collaboration, Siemens Healthineers Ltd, Shanghai, China, 4Department of Cardiology, West China Hospital, Chengdu, China

Primary aldosteronism (PA) increases cardiovascular morbidity. In order to elucidate the early features of heart damage of PA, we used the cardiac MRI and T1 mapping technique to evaluate and compare cardiac function and myocardium changes in PA and essential hypertension (EH) patients. Our results found that the PA patients had higher native T1 than the EH group, while other functional parameters had no significant differences between two groups. The change of myocardium was earlier in PA patients than in EH patients, suggesting that it is mainly due to myocardial fibrosis induced by inappropriate secretion of aldosterone.

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