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Abstract #2088

Pancreatic iron and cardiac iron and function in patients with thalassemia intermedia

Antonella Meloni1, Laura Pistoia1, Vincenzo Positano1, Giuseppe Peritore2, Paolo Preziosi3, Ada Riva4, Massimiliano Missere5, Antonino Vallone6, Valentina Carrai7, F. Mehtap Pasin3, Mauro Murgia8, and Alessia Pepe1
1MRI Unit, Fondazione G. Monasterio CNR-Regione Toscana, Pisa, Italy, 2"ARNAS" Civico, Di Cristina Benfratelli, Palermo, Italy, 3Ospedale "Sandro Pertini", Roma, Italy, 4Ospedale “SS. Annunziata” ASL Taranto, Taranto, Italy, 5Fondazione di Ricerca e Cura "Giovanni Paolo II", Campobasso, Italy, 6Azienda Ospedaliera "Garibaldi" Presidio Ospedaliero Nesima, Catania, Italy, 7Universitaria Careggi, Firenze, Italy, 8Ospedale San Martino di Oristano, Oristano, Italy

In patients with thalassemia intermedia (TI) pancreatic iron overload is frequent (58.1%), especially if regular transfusions are performed. Pancreatic T2* values were correlated with cardiac T2* values and a normal pancreas T2* showed negative predictive value of 100% for cardiac iron. Global pancreas T2* values were not correlated to biventricular volumes and ejection fraction or to myocardial fibrosis.

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