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Abstract #2090

Dual-contrast and dual-phase first-pass myocardial perfusion using simultaneous multi-slice imaging

Giulio Ferrazzi1, Sarah McElroy1, Radhouene Neji1,2, Karl Kunze1,2, Muhummad Sohaib Nazir1, Peter Speier3, Daniel Stäb4, Christoph Forman3, Reza Razavi1, Amedeo Chiribiri1, and Sébastien Roujol1
1School of Biomedical Engineering and Imaging Sciences, King's College London, London, United Kingdom, 2MR Research Collaborations, Siemens Healthcare Limited, Frimley, United Kingdom, 3Cardiovascular MR predevelopment, Siemens Healthcare GmbH, Erlangen, Germany, 4MR Research Collaborations, Siemens Healthcare Limited, Melbourne, Australia

The clinical need of covering multiple slices in myocardial perfusion constrains the saturation delay time to be short. However, this may be suboptimal in terms of myocardial/defect tissue contrast and blood/myocardium signal ratios. Moreover, it is not possible to acquire the same slice twice, and all slices are at different cardiac phases.

In this study, we develop a perfusion sequence which provides dual phase and dual contrast data using simultaneous multi-slice at two different saturation delay times. Simulations and in-vivo data acquired in patients demonstrated a 150% increase of myocardial/defect contrast, and decreased blood/myocardium signal ratio by 60 to 80%.

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