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Abstract #2091

Myocardial perfusion quantification by cardiovascular magnetic resonance is significantly affected by the arterial input sampling location

Xenios Milidonis1, Russell Franks1, Kajol Verma1, Torben Schneider1,2, Javier Sánchez-González3, Sven Plein1, and Amedeo Chiribiri1
1King's College London, London, United Kingdom, 2Philips Healthcare, Guilford, United Kingdom, 3Philips Healthcare, Madrid, Spain

The arterial input function (AIF) describes the contrast agent input to the myocardium and is required for blood flow quantification. However, the impact of the AIF sampling location on quantification by cardiovascular magnetic resonance and the diagnosis of coronary artery disease (CAD) has yet to be determined. In this study, perfusion imaging was performed in patients with suspected CAD and blood flow was quantified for seven different locations. It was found that the sampling location has a significant impact on blood flow measurements, while the ascending aorta led to the most accurate prediction of inducible perfusion abnormalities.

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