Abstract #2092

The importance of myocardial SNR in myocardial blood flow quantification derived from first-pass cardiac perfusion CMR

Sungtak Hong¹, Kyungpyo Hong², Li-Yueh Hsu³, Daniel C Lee⁴, and Daniel Kim¹

¹Radiology, Northwestern University, Chicago, IL, United States, ²Translational and Molecular Imaging Institute and Department of Radiology, Icahn School of Medicine at Mount Sinai, New York, NY, United States, ³National Heart, Lung, and Blood Institute, National Institutes of Health, Bethesda, MD, United States, ⁴Division of Cardiology, Internal Medicine, Northwestern University, Chicago, IL, United States

We have recently developed a perfusion CMR pulse sequence using golden angle radial acquisitions and CS reconstruction. The radial k-space sampling allows retrospective manipulation of saturation-recovery time (TS) using k-space weighted image contrast (KWIC) filtering. This study was conducted to determine the importance of SNR in myocardial blood flow quantification derived from cardiac perfusion CMR. Our analysis shows that mean resting MBF values decreases with TS, where the result with the highest TS = 95 ms agrees best with literature value reported by cardiac PET studies.

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