Abstract #2100

Pressure-volume Relationship by Stress Cardiovascular Magnetic Resonance: feasibility and clinical implications

Antonella Meloni¹, Antonio De Luca², Cinzia Nugara³, Chiara Cappelletto², Camilla Cavallaro⁴, Giovanni Donato Aquaro¹, Chrysanthos Grigoratos¹, Giancarlo Todiere¹, Andrea Barison¹, Gianfranco Sinagra², Giuseppina Novo³, Germano Di Sciascio⁴, and Alessia Pepe¹

¹MRI Unit, Fondazione G. Monasterio CNR-Regione Toscana, Pisa, Italy, ²University of Trieste, Trieste, Italy, ³University of Palermo, Palermo, Italy, ⁴Università Campus Bio-Medico, Roma, Italy

We showed for the first time that the ΔESPVR index, an index of myocardial contractile function easily obtained during routine stress echocardiography, can be noninvasively calculated during a dipyridamole stress-CMR exam. The ΔESPVR index was independent from baseline LV dimensions and function while it was lower in patients with myocardial fibrosis and in patients with abnormal stress CMR. At receiver-operating characteristic curve analysis, a ΔESPVR<0.02 predicted the presence of future cardiac events, being useful for additional prognostic stratification.

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