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Abstract #2100

Pressure-volume Relationship by Stress Cardiovascular Magnetic Resonance: feasibility and clinical implications

Antonella Meloni1, Antonio De Luca2, Cinzia Nugara3, Chiara Cappelletto2, Camilla Cavallaro4, Giovanni Donato Aquaro1, Chrysanthos Grigoratos1, Giancarlo Todiere1, Andrea Barison1, Gianfranco Sinagra2, Giuseppina Novo3, Germano Di Sciascio4, and Alessia Pepe1
1MRI Unit, Fondazione G. Monasterio CNR-Regione Toscana, Pisa, Italy, 2University of Trieste, Trieste, Italy, 3University of Palermo, Palermo, Italy, 4Università Campus Bio-Medico, Roma, Italy

We showed for the first time that the ΔESPVR index, an index of myocardial contractile function easily obtained during routine stress echocardiography, can be noninvasively calculated during a dipyridamole stress-CMR exam. The ΔESPVR index was independent from baseline LV dimensions and function while it was lower in patients with myocardial fibrosis and in patients with abnormal stress CMR. At receiver-operating characteristic curve analysis, a ΔESPVR<0.02 predicted the presence of future cardiac events, being useful for additional prognostic stratification.

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