Abstract #2115

Quantifying the impact of pulmonary artery stent interventions on ventricular flow dynamics with 4D Flow MRI

Ryan Pewowaruk¹, Cody Johnson², Chris Francois², Luke Lamers², and Alejandro Roldán-Alzate²

¹Biomedical Engineering, University of Wisconsin - Madison, Madison, WI, United States, ²University of Wisconsin - Madison, Madison, WI, United States

In a swine model of PAS, this study assessed the effects of early versus delayed stent interventions using 4D Flow MRI. Early and Delayed interventions were both effective but no differences between early and delayed interventions were observed. 4D Flow MRI measured inefficient LV and RV flow in the PAS group and an association was found between EF and vorticity. If confirmed in larger studies, these results provide physiological insight into PAS and congenital heart disease and also highlight the sensitivity of 4D Flow MRI biomarkers to ventricular dysfunction.

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