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Abstract #2215

Sodium MRI of the Rat Heart at 9.4 T using a Quadrature Birdcage

Laura Boehmert1, Helmar Waiczies2, Andre Kuehne2, Celal Oezerdem1, Sonia Waiczies1, Ludger Starke1, Min-Chi Ku1, Andreas Pohlmann1, Paula Ramos Delgado1, Erdmann Seeliger3, and Thoralf Niendorf1,2,4,5
1Berlin Ultrahigh Field Facility (B.U.F.F.), Max Delbrück Center for Molecular Medicine in the Helmholtz Association, Berlin, Germany, 2MRI.TOOLS GmbH, Berlin, Germany, 3Institute of Vegetative Physiology, Charité University Medicine, Berlin, Germany, 4DZHK (German Centre for Cardiovascular Research), partner site Berlin, Berlin, Germany, 5Experimental and Clinical Research Center, a joint cooperation between the Charité Medical Faculty and the Max Delbrück Center for Molecular Medicine, Berlin, Germany

We propose probing of tissue sodium concentrations in the heart using 23Na MRI for adding a very useful dimension to our understanding of cardiac disorders. Changes in the sodium concentration might be indicative of early pathophysiological changes in such diseases. This work focuses on the development, evaluation and application of a quadrature birdcage RF resonator tailored for cardiac 23Na MRI at 9.4T with the goal to provide a uniform excitation profile.

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