Abstract #2215

Sodium MRI of the Rat Heart at 9.4 T using a Quadrature Birdcage

Laura Boehmert¹, Helmar Waiczies², Andre Kuehne², Celal Oezerdem¹, Sonia Waiczies¹, Ludger Starke¹, Min-Chi Ku¹, Andreas Pohlmann¹, Paula Ramos Delgado¹, Erdmann Seeliger³, and Thoralf Niendorf^1,2,4,5

¹Berlin Ultrahigh Field Facility (B.U.F.F.), Max Delbrück Center for Molecular Medicine in the Helmholtz Association, Berlin, Germany, ²MRI.TOOLS GmbH, Berlin, Germany, ³Institute of Vegetative Physiology, Charité University Medicine, Berlin, Germany, ⁴DZHK (German Centre for Cardiovascular Research), partner site Berlin, Berlin, Germany, ⁵Experimental and Clinical Research Center, a joint cooperation between the Charité Medical Faculty and the Max Delbrück Center for Molecular Medicine, Berlin, Germany

We propose probing of tissue sodium concentrations in the heart using ²³Na MRI for adding a very useful dimension to our understanding of cardiac disorders. Changes in the sodium concentration might be indicative of early pathophysiological changes in such diseases. This work focuses on the development, evaluation and application of a quadrature birdcage RF resonator tailored for cardiac ²³Na MRI at 9.4T with the goal to provide a uniform excitation profile.

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