Conventional 2D LGE often suffers from poor scar-to-blood contrast and limited spatial resolution. While 3D methods are known for their superior spatial resolution, our earlier proposed dark-blood LGE without additional magnetization preparation enables improved scar-to-blood contrast. In the present study we sought to assess the effect of a slowly increasing, dynamic inversion time on left-ventricular blood-pool suppression in a high-resolution isotropic 3D dark-blood LGE acquisition, and compare it against a conventional, fixed inversion time. Our findings show that such a dynamic inversion time significantly improves blood-pool suppression and thereby maximizes the dark-blood contrast mechanism for improved detection of myocardial scarring.
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