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Abstract #2246

The effect of a dynamic inversion time in high-resolution isotropic 3D dark-blood LGE without additional magnetization preparation

Robert J Holtackers1,2,3, Suzanne Gommers1,2, Caroline M van de Heyning3,4, Jouke Smink5, Amedeo Chiribiri3, Joachim E Wildberger1,2, and Rachel ter Bekke2,6
1Department of Radiology & Nuclear Medicine, Maastricht University Medical Centre, Maastricht, Netherlands, 2CARIM School of Cardiovascular Diseases, Maastricht University, Maastricht, Netherlands, 3School of Biomedical Engineering and Imaging Sciences, King’s College London, London, United Kingdom, 4Department of Cardiology, Antwerp University Hospital, Antwerp, Belgium, 5Philips Healthcare, Best, Netherlands, 6Department of Cardiology, Maastricht University Medical Centre, Maastricht, Netherlands

Conventional 2D LGE often suffers from poor scar-to-blood contrast and limited spatial resolution. While 3D methods are known for their superior spatial resolution, our earlier proposed dark-blood LGE without additional magnetization preparation enables improved scar-to-blood contrast. In the present study we sought to assess the effect of a slowly increasing, dynamic inversion time on left-ventricular blood-pool suppression in a high-resolution isotropic 3D dark-blood LGE acquisition, and compare it against a conventional, fixed inversion time. Our findings show that such a dynamic inversion time significantly improves blood-pool suppression and thereby maximizes the dark-blood contrast mechanism for improved detection of myocardial scarring.

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