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Abstract #2245

Detection of atrial scar using 3D high-resolution dark-blood phase sensitive inversion recovery imaging

Dongyue Si1, Yanfang Wu2, Jie Yin2, Rui Guo3, Jingjing Xiao4, Bowei Liu1, Xue Lin2, Peng Gao2, Deyan Yang2, Quan Fang2, Jianwen Luo1, Daniel A. Herzka5,6, and Haiyan Ding1
1Center for Biomedical Imaging Research (CBIR), Department of Biomedical Engineering, School of Medicine, Tsinghua University, Beijing, China, 2Department of Cardiology, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing, China, 3Department of Medicine, Beth Israel Deaconess Medical Center and Harvard Medical School, Boston, MA, United States, 4Department of Medical Engineering, Xinqiao Hosptial, Army Medical University, Chongqing, China, 5Department of Biomedical Engineering, Johns Hopkins School of Medicine, Baltimore, MD, United States, 6Cardiovascular Interventional Program, National Heart, Lung, and Blood Institute, National Institutes of Health, Bethesda, MD, United States

Radiofrequency ablation (RFA) is a first-line treatment for controlling atrial fibrillation (AF). Visualizing fibrotic tissues as well as the surrounding anatomical structure could improve the delivery of therapy. In this work, an independent navigator-gated three-dimensional dark-blood phase-sensitive inversion recovery sequence was developed for atrial visualization. Dark-blood was achieved by optimizing inversion recovery and T2-preparation timing. Preliminary results from in vivo imaging in patients with AF post RFA demonstrate that the proposed technique can clearly visualize the atrial wall and scar formation. Both dark blood contrast and high resolution (1.25×1.25×3 mm3) were achieved.

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