Abstract #2245

Detection of atrial scar using 3D high-resolution dark-blood phase sensitive inversion recovery imaging

Dongyue Si¹, Yanfang Wu², Jie Yin², Rui Guo³, Jingjing Xiao⁴, Bowei Liu¹, Xue Lin², Peng Gao², Deyan Yang², Quan Fang², Jianwen Luo¹, Daniel A. Herzka^5,6, and Haiyan Ding¹

¹Center for Biomedical Imaging Research (CBIR), Department of Biomedical Engineering, School of Medicine, Tsinghua University, Beijing, China, ²Department of Cardiology, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing, China, ³Department of Medicine, Beth Israel Deaconess Medical Center and Harvard Medical School, Boston, MA, United States, ⁴Department of Medical Engineering, Xinqiao Hosptial, Army Medical University, Chongqing, China, ⁵Department of Biomedical Engineering, Johns Hopkins School of Medicine, Baltimore, MD, United States, ⁶Cardiovascular Interventional Program, National Heart, Lung, and Blood Institute, National Institutes of Health, Bethesda, MD, United States

Radiofrequency ablation (RFA) is a first-line treatment for controlling atrial fibrillation (AF). Visualizing fibrotic tissues as well as the surrounding anatomical structure could improve the delivery of therapy. In this work, an independent navigator-gated three-dimensional dark-blood phase-sensitive inversion recovery sequence was developed for atrial visualization. Dark-blood was achieved by optimizing inversion recovery and T₂-preparation timing. Preliminary results from in vivo imaging in patients with AF post RFA demonstrate that the proposed technique can clearly visualize the atrial wall and scar formation. Both dark blood contrast and high resolution (1.25×1.25×3 mm³) were achieved.

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