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Abstract #2264

Flow measurement with time of flight (TOF) in patients undergoing carotid revascularization: A comparison with arterial spin labeling (ASL)

Zhensen Chen1, Li Chen2, Manabu Shirakawa1, Wenjin Liu1, Dakota Ortega1, Jinmei Chen1, Niranjan Balu1, Theodore Trouard3, Thomas S Hatsukami4, Wei Zhou5, and Chun Yuan1
1Radiology, University of Washington, Seattle, WA, United States, 2Electrical and computer engineering, University of Washington, Seattle, WA, United States, 3Biomedical Engineering, University of Arizona, Tuscon, AZ, United States, 4Surgery, University of Washington, Seattle, WA, United States, 5Surgery, University of Arizona, Tuscon, AZ, United States

In this study, we assessed the potential of using vasculature features extracted from TOF images as surrogate markers of intracranial blood flow in patients undergoing carotid revascularization surgery and MR imaging prior to, within 48 hours after and 6 months after surgery. The intracranial vasculature features, including total volume, total length and total number of branches etc., on TOF images were extracted using a novel tool named iCafe, and then compared with arterial spin labeling (ASL) cerebral blood flow (CBF) measurement. The results show that TOF-iCafe vasculature features have similar behaviors as ASL CBF over the time points.

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