4D Flow MRI is a technique that can characterize vascular structure and hemodynamics. Compared with SENSE, Compressed SENSE can further reduce scanning time using the sparse characteristics of MR images. This study aims to investigate the feasibility of 4D Flow MRI with Compressed SENSE by comparing with 4D Flow MRI with SENSE. 4D Flow dynamic angiography of hepatic portal vein using SENSE and Compressed SENSE could be completed within 5 minutes with optimized parameters. The scanning time of Compressed SENSE 4D Flow was shorter than that of SENSE 4D Flow.