Abstract #2268

Method for Comprehensive Analysis of Vascular Geometry and Fluid Dynamics Using MRI

Dominik Daniel Gabbert¹, Arash Kheradvar², Michael Jerosch-Herold³, Thekla Oechtering⁴, Felix Wadle¹, Anselm Sebastian Uebing¹, Hans-Heiner Kramer¹, Inga Voges¹, and Carsten Rickers¹

¹Department of Congenital Heart Disease and Pediatric Cardiology, University Hospital Schleswig-Holstein, Kiel, Germany, ²The Edwards Lifesciences Center for Advanced Cardiovascular Technology, University of California, Irvine, CA, United States, ³Harvard Medical School, Brigham and Women’s Hospital, Boston, MA, United States, ⁴Department of Radiology and Nuclear Medicine, University Hospital Schleswig-Holstein, Lübeck, Germany

Many secondary flow patterns in the large vessels have been shown to represent significant pathophysiological phenomena. However, the computational cost to analyze a large number of quantities usually discourage the use of these parameters for clinical decision making given the limited computing resources in clinical settings. We describe a novel postprocessing method for comprehensive analysis of vascular anatomy and fluid dynamics based on 4D Flow MRI. The method defines a multi-dimensional feature space built from a few complementary fluid dynamics building blocks to efficiently determine a large number of anatomic and fluid dynamics parameters in the course of a vessel.

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