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Abstract #2268

Method for Comprehensive Analysis of Vascular Geometry and Fluid Dynamics Using MRI

Dominik Daniel Gabbert1, Arash Kheradvar2, Michael Jerosch-Herold3, Thekla Oechtering4, Felix Wadle1, Anselm Sebastian Uebing1, Hans-Heiner Kramer1, Inga Voges1, and Carsten Rickers1
1Department of Congenital Heart Disease and Pediatric Cardiology, University Hospital Schleswig-Holstein, Kiel, Germany, 2The Edwards Lifesciences Center for Advanced Cardiovascular Technology, University of California, Irvine, CA, United States, 3Harvard Medical School, Brigham and Women’s Hospital, Boston, MA, United States, 4Department of Radiology and Nuclear Medicine, University Hospital Schleswig-Holstein, Lübeck, Germany

Many secondary flow patterns in the large vessels have been shown to represent significant pathophysiological phenomena. However, the computational cost to analyze a large number of quantities usually discourage the use of these parameters for clinical decision making given the limited computing resources in clinical settings. We describe a novel postprocessing method for comprehensive analysis of vascular anatomy and fluid dynamics based on 4D Flow MRI. The method defines a multi-dimensional feature space built from a few complementary fluid dynamics building blocks to efficiently determine a large number of anatomic and fluid dynamics parameters in the course of a vessel.

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