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Abstract #2312

Applicability of automated cardiac phase sorting for phase resolved functional lung (PREFUL) MRI

Lea Behrendt1,2, Andreas Voskrebenzev1,2, Filip Klimeš1,2, Marcel Gutberlet1,2, Hinrich Winther1, Till Kaireit1,2, Tawfik Moher Alsady1,2, Gesa Pöhler1,2, Frank Wacker1,2, and Jens Vogel-Claussen1,2
1Institute of Diagnostic and Interventional Radiology, Hannover Medical School, Hannover, Germany, 2Biomedical Research in Endstage and Obstructive Lung Disease Hannover (BREATH), German Center for Lung Research (DZL), Hannover, Germany

Phase-resolved functional lung (PREFUL) MRI is a promising contrast agent-free 1H method to derive information about perfusion dynamics in free breathing. The analysis includes the segmentation of a main vessel to determine the perfusion phase for reconstruction of a full cardiac cycle. Since manual segmentation can be challenging and time-consuming, an algorithm for automated phase sorting is desirable. In this study such an algorithm is proposed, tested in 34 patients with CF and CTEPH and compared to manual phase sorting. The algorithm was able to perform segmentation in all cases and showed improved phase sorting compared to manual segmentation.

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