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Abstract #2364

Quantify the Progression of Acute Lung Injury Induced by Lipopolysaccharide with Hyperpolarized 129Xe MR

Haidong Li1, Ming Zhang1, Hongchuang Li1, Xiuchao Zhao1, Yeqing Han1, Xianping Sun1, Chaohui Ye1, and Xin Zhou1
1National Center for Magnetic Resonance in Wuhan, Wuhan Institute of Physics and Mathematics, Innovation Academy of Precision Measurement Science and Technology, Chinese Academy of Sciences-Wuhan National Laboratory for Optoelectronics, Wuhan, China

CT and PET should not be performed on patient repeatedly in short-term for monitoring the progression of diseases since the ionizing radiation and radioactivity. Herein, we tried to demonstrate the feasibility of hyperpolarized 129Xe MR for monitoring the progression of acute lung injury (ALI) in rats. Our results indicated hyperpolarized 129Xe MR has the potential to monitor the progression of ALI in rats.

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