Abstract #2378

Quantitative Bilateral Sodium and Proton Breast Imaging at 3T

Gabrielle C Baxter¹, Mary A McLean², Joshua D Kaggie¹, Frank Riemer³, Ferdia A Gallagher¹, Andrew D James^4,5, Aneurin J Kennerley^5,6, Rolf F Schulte⁷, William J Brackenbury^4,5, and Fiona J Gilbert¹

¹Department of Radiology, University of Cambridge, Cambridge, United Kingdom, ²Cancer Research UK, Cambridge, United Kingdom, ³Department of Radiology, Haukeland University Hospital, Bergen, Norway, ⁴Department of Biology, University of York, York, United Kingdom, ⁵York Biomedical Research Institute, University of York, York, United Kingdom, ⁶Department of Chemistry, University of York, York, United Kingdom, ⁷GE Healthcare, Munich, Germany

Sodium (²³Na)-MRI was performed using a dual-tuned bilateral ²³Na/¹H breast coil on four healthy volunteers. Images acquired using ²³Na-MRI show a relationship between sodium concentration and diffusion properties of breast tissue. Sodium signal variations due to mild flip angle non-uniformity were observed between left and right breasts. After correction using B₁ mapping, tissue sodium concentration (TSC) maps were more closely matched between breasts.

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