Advanced data acquisition and reconstruction methods have been proposed to improve temporal and spatial resolution DCE imaging for breast. However, validation and comparison of these methods against a known truth is challenging. In this work we propose a digital reference object for breast pharmacokinetic simulation to evaluate different advanced reconstructions including MOCCO and iGRASP. The approach allowed comparison of the reconstructed temporal characteristics including pharmacokinetic analysis using different reconstruction parameters against the assigned ground truth. Spatial sharpness was also measured to compare with reference fully sampled images.