Meeting Banner
Abstract #2385

Portable NMR for quantification of breast density and tissue composition: from proof-of-concept in vitro to trials in vivo

Konstantin I. Momot1, Honor J. Hugo 2, Xuan Huang2, Tony Blick2, Tonima S. Ali3, Monique C. Tourell3, Thomas Lloyd4, and Erik W. Thompson2
1School of Chemistry and Physics, Queensland University of Technology, Brisbane, Australia, 2Queensland University of Technology, Brisbane, Australia, 3University of Queensland, Brisbane, Australia, 4Princess Alexandra Hospital, Brisbane, Australia

Elevated mammographic density (MD) is a significant independent risk factor for breast cancer and a source of masking in X-ray mammography. Availability of a low-cost, non-ionising measurement technique for quantitative assessment of MD would be valuable both in therapeutic and research contexts. We demonstrate that Portable NMR, a low-cost technique based on the same physics as MRI, represents a reliable approach to quantification of MD in excised breast tissue samples in vitro. We also present the initial results of an observational trial in healthy volunteers, which show that Portable NMR has a great potential for quantification of MD in vivo.

This abstract and the presentation materials are available to 2020 meeting attendees and eLibrary customers only; a login is required.

Join Here