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Abstract #2401

Visualize the micro-hemorrhage of HCC through SWI and intravoxel incoherent motions to predict the microvascular invasion

Zhijun Geng1, Yunfei Zhang2, Hui Li1, Jing Zhao1, Sihui Zeng1, Cheng Zhang1, Chuanmiao Xie1, and Yongming Dai2
1Sun Yat-sen University Cancer Center, Guangzhou, China, 2United Imaging Healthcare, Shanghai, China

Tightly correlated with the prognosis, microvascular invasion (MVI) serves as one significant predictor determining the clinical management. Abnormal angiogenesis, one typical character during carcinogenesis, can lead to the abnormal micro-vessel manifestations including micro-hemorrhage and more, which may correlate with another abnormal vascular manifestations—MVI. Hence, this research aims to predict the MVI via visualizing the intra-tumor hemorrhage with susceptibility weighted imaging (SWI) widely proven to be powerful for imaging hemorrhage and IVIM hypothesized to be effective for visualizing the hemorrhage via quantifying the abnormal perfusion. The results displayed that visualizing the micro-hemorrhage holds great potential for predicting MVI of HCC.

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