Tightly correlated with the prognosis, microvascular invasion (MVI) serves as one significant predictor determining the clinical management. Abnormal angiogenesis, one typical character during carcinogenesis, can lead to the abnormal micro-vessel manifestations including micro-hemorrhage and more, which may correlate with another abnormal vascular manifestations—MVI. Hence, this research aims to predict the MVI via visualizing the intra-tumor hemorrhage with susceptibility weighted imaging (SWI) widely proven to be powerful for imaging hemorrhage and IVIM hypothesized to be effective for visualizing the hemorrhage via quantifying the abnormal perfusion. The results displayed that visualizing the micro-hemorrhage holds great potential for predicting MVI of HCC.
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