Abstract #2402

3D ROI Histogram Based on Intravoxel Incoherent Motion for Preoperative Evaluation of Pathological Differentiation of the Hepatocellular Carcinoma

Zhe Zhang¹, Ailian Liu¹, Ying Zhao¹, Jingjun Wu¹, Nan Wang¹, Dahua Cui¹, Tao Lin¹, Qingwei Song¹, Xin Li¹, Tingfan Wu¹, and Yan Guo¹

¹Department of Radiology, the First Affiliated Hospital of Dalian Medical University, Dalian, China, Dalian, China

The purpose of this study was to preoperatively evaluate pathological differentiation of the whole hepatocellular carcinoma (HCC) by 3D ROI histogram of ADC, D, D* and f. The results showed that 3D ROI histogram of ADC, D can identify poor differentiated HCC. The D-5th achieved the highest AUC values (AUC: 0.778; sensitivity: 66.7%; specificity: 78.4%). Although there was no significant difference between AUC of 3D ROI histogram and routine ROI, 3D ROI histogram can reflect the heterogeneity to evaluate the differentiation of the whole tumor.

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