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Abstract #2402

3D ROI Histogram Based on Intravoxel Incoherent Motion for Preoperative Evaluation of Pathological Differentiation of the Hepatocellular Carcinoma

Zhe Zhang1, Ailian Liu1, Ying Zhao1, Jingjun Wu1, Nan Wang1, Dahua Cui1, Tao Lin1, Qingwei Song1, Xin Li1, Tingfan Wu1, and Yan Guo1
1Department of Radiology, the First Affiliated Hospital of Dalian Medical University, Dalian, China, Dalian, China

The purpose of this study was to preoperatively evaluate pathological differentiation of the whole hepatocellular carcinoma (HCC) by 3D ROI histogram of ADC, D, D* and f. The results showed that 3D ROI histogram of ADC, D can identify poor differentiated HCC. The D-5th achieved the highest AUC values (AUC: 0.778; sensitivity: 66.7%; specificity: 78.4%). Although there was no significant difference between AUC of 3D ROI histogram and routine ROI, 3D ROI histogram can reflect the heterogeneity to evaluate the differentiation of the whole tumor.

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