Microvascular invasion (MVI) is one of the most important factors for the recurrence of hepatocellular carcinoma (HCC), however, accurate preoperative evaluation of MVI is quietly difficult because of the controversy results caused by the conventional imaging features. Compared with diffusion-weighted imaging (DWI), Intravoxel incoherent motion (IVIM) diffusion-weighted MR imaging could better characterize heterogeneity and irregularity of tissue components, and thus may have the potential to better evaluate MVI. In this study, we prospectively determine the usefulness of IVIM parameters and conventional radiologic features for preoperative prediction of MVI in patients with HCC.
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