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Abstract #2418

The Value of Obtaining Incremental Cores in MRI Guided Prostate Biopsy

Nicole Seyfried1, Amr Mahran1,2, Ananya Panda3, Verena Obmann4, Christina Buzzy1,2, Yun Jiang5, Katie Wright5, Dean Nakamoto6, Indravadan Patel7, Britt Conroy1,2, Lee Ponsky1,2, and Vikas Gulani5
1School of Medicine, Case Western Reserve University, Cleveland, OH, United States, 2Urology Institute, University Hospitals, Cleveland, OH, United States, 3Radiology, Mayo Clinic, Rochester, MN, United States, 4Department of Diagnostic, Interventional and Pediatric Radiology, Bern University Hospital, Bern, Switzerland, 5Department of Radiology, University of Michigan, Ann Arbor, MI, United States, 6Radiology, Louis Stokes Cleveland VA Medical Center, Cleveland, OH, United States, 7Radiology, Mayo Clinic, Scottsdale, AZ, United States

The value of incremental biopsy cores during in-gantry MRI-guided targeted prostate biopsy for prostate cancer diagnosis was examined. 135 patients with 175 lesions underwent in-gantry targeted prostate biopsy and the rates of pathology upgrading for sequential cores were determined. Significant upgrading was observed when increasing from 1 to 2 cores and from 2 to 3 cores, but not from core 3 to 4. Higher Prostate Imaging Reporting and Data System (PI-RADS) Version 2.0 score and anteriorly located lesions were more likely to result in an upgrade.

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