Abstract #2418

The Value of Obtaining Incremental Cores in MRI Guided Prostate Biopsy

Nicole Seyfried¹, Amr Mahran^1,2, Ananya Panda³, Verena Obmann⁴, Christina Buzzy^1,2, Yun Jiang⁵, Katie Wright⁵, Dean Nakamoto⁶, Indravadan Patel⁷, Britt Conroy^1,2, Lee Ponsky^1,2, and Vikas Gulani⁵

¹School of Medicine, Case Western Reserve University, Cleveland, OH, United States, ²Urology Institute, University Hospitals, Cleveland, OH, United States, ³Radiology, Mayo Clinic, Rochester, MN, United States, ⁴Department of Diagnostic, Interventional and Pediatric Radiology, Bern University Hospital, Bern, Switzerland, ⁵Department of Radiology, University of Michigan, Ann Arbor, MI, United States, ⁶Radiology, Louis Stokes Cleveland VA Medical Center, Cleveland, OH, United States, ⁷Radiology, Mayo Clinic, Scottsdale, AZ, United States

The value of incremental biopsy cores during in-gantry MRI-guided targeted prostate biopsy for prostate cancer diagnosis was examined. 135 patients with 175 lesions underwent in-gantry targeted prostate biopsy and the rates of pathology upgrading for sequential cores were determined. Significant upgrading was observed when increasing from 1 to 2 cores and from 2 to 3 cores, but not from core 3 to 4. Higher Prostate Imaging Reporting and Data System (PI-RADS) Version 2.0 score and anteriorly located lesions were more likely to result in an upgrade.

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