Abstract #2427

Developing Hybrid Multidimensional MRI without an endorectal coil for the detection of prostate cancer: a feasibility study

Durgesh Kumar Dwivedi^1,2, Aritrick Chatterjee¹, Ajit Devaraj³, Ambereen Yousuf¹, Gregory S Karczmar¹, Tatjana Antic⁴, Scott Eggener⁵, and Aytekin Oto¹

¹Department of Radiology, University of Chicago, Chicago, IL, United States, ²Department of Radiodiagnosis, King George's Medical University, Lucknow, India, ³Philips Research North America, Cambridge, MA, United States, ⁴Department of Pathology, University of Chicago, Chicago, IL, United States, ⁵Department of Urology, University of Chicago, Chicago, IL, United States

There are conflicting reports on the use of endorectal coil in the detection of prostate cancer at 3T due to increased patient discomfort and susceptibility artifacts. The purpose of the present study was to evaluate the feasibility of Hybrid Multidimensional MRI (HM-MRI) without an endorectal coil (using pelvic phased-array coil only) in the detection of prostate cancer (PCa) and to calculate fractional volumes of prostatic tissue composition, non-invasively. A non-endorectal coil HM-MRI is feasible. We obtained a significant difference in epithelium volume between normal and PCa (p = 0.02), however stromal and luminal volume did not reach a significance level.

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