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Abstract #2433

Comparative study of APTw combined with T2 mapping quantitative imaging in patients of rectal cancer with and without chemotherapy

Anliang Chen1, Ailian Liu1, Xuedong Wang1, Yunsong Liu1, Jingjun Wu1, Qingwei Song1, Renwang Pu1, Jiazheng Wang2, Zhiwei Shen2, and Liangjie Lin2
1Radiology, The First Affiliated Hospital of Dalian Medical University, Dalian, China, 2Philips Healthcare, Beijing, China

Amide proton transfer-weighted (APTw) imaging can be used to assess changes of intracellular protein concentration and the pH value.And the T2 mapping allows non-invasive visualization and quantification of tissue composition. Here, weaimsto explore the value of APTw imaging in combination with T2 mapping in comparative analysesof rental cancer with and without chemotherapy. Results indicated that a ultrahigh diagnostic efficacy (AUC: 1.000; sensitivity: 100%; specificity: 100%) was achieved with combination of APT and T2 values.

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