Abstract #2433

Comparative study of APTw combined with T2 mapping quantitative imaging in patients of rectal cancer with and without chemotherapy

Anliang Chen¹, Ailian Liu¹, Xuedong Wang¹, Yunsong Liu¹, Jingjun Wu¹, Qingwei Song¹, Renwang Pu¹, Jiazheng Wang², Zhiwei Shen², and Liangjie Lin²

¹Radiology, The First Affiliated Hospital of Dalian Medical University, Dalian, China, ²Philips Healthcare, Beijing, China

Amide proton transfer-weighted (APTw) imaging can be used to assess changes of intracellular protein concentration and the pH value.And the T2 mapping allows non-invasive visualization and quantification of tissue composition. Here, weaimsto explore the value of APTw imaging in combination with T2 mapping in comparative analysesof rental cancer with and without chemotherapy. Results indicated that a ultrahigh diagnostic efficacy (AUC: 1.000; sensitivity: 100%; specificity: 100%) was achieved with combination of APT and T2 values.

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