Abstract #2434

Value of texture analysis based on DWI with multiple b-values for evaluation of tumor heterogeneity in rectal cancer patients

Jingjun Wu¹, Ailian Liu¹, Jiazheng Wang², Zhongping Zhang², Anliang Chen¹, Xuedong Wang¹, Yunsong Liu¹, Lihua Chen¹, Qingwei Song¹, Renwang Pu¹, and Bingbing Gao¹

¹Department of Radiology, the First Affiliated Hospital of Dalian Medical University, Dalian, China, ²Philips Healthcare, Beijing, China

Rectal cancer is the third most common cancer and the second cause of cancer-related death worldwide. DWI is now recommended as a routine addition to the MRI protocol for the assessment of rectal cancer. However, the effect of the b-value on the diagnostic performance has not yet been explored. The current study aims to evaluate the value of texture analysis based on DWI with different B values to evaluate the heterogeneity of rectal cancer patients. The skewness and kurtosis were all significantly different in DWI with different B values, and they were obviously changed when B reached 800.

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