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Abstract #2434

Value of texture analysis based on DWI with multiple b-values for evaluation of tumor heterogeneity in rectal cancer patients

Jingjun Wu1, Ailian Liu1, Jiazheng Wang2, Zhongping Zhang2, Anliang Chen1, Xuedong Wang1, Yunsong Liu1, Lihua Chen1, Qingwei Song1, Renwang Pu1, and Bingbing Gao1
1Department of Radiology, the First Affiliated Hospital of Dalian Medical University, Dalian, China, 2Philips Healthcare, Beijing, China

Rectal cancer is the third most common cancer and the second cause of cancer-related death worldwide. DWI is now recommended as a routine addition to the MRI protocol for the assessment of rectal cancer. However, the effect of the b-value on the diagnostic performance has not yet been explored. The current study aims to evaluate the value of texture analysis based on DWI with different B values to evaluate the heterogeneity of rectal cancer patients. The skewness and kurtosis were all significantly different in DWI with different B values, and they were obviously changed when B reached 800.

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