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Abstract #2462

Non-invasive assessment of progressive changesĀ in aristolochic acid (AA) induced AKI with T2 mapping

Yingjie Mei1,2, Guixiang Yang3, Yihao Guo1,4, Kaixuan Zhao1,4, Chenggong Yan3, Yikai Xu3, and Yanqiu Feng1,4
1Guangdong Provincial Key Laboratory of Medical Image Processing, Southern Medical University, Guang Zhou, China, 2Philips Healthcare, Guang Zhou, China, 3Department of Medical Imaging Center, Nanfang Hospital, Southern Medical University, Guangzhou, China, 4School of Biomedical Engineering, Southern Medical University, Guang Zhou, China

Cases of Aristolochic acid nephropathy (AAN) have been reported worldwide, yet no serum or urinary biomarkers have been shown to have clinical utility in detection of AAN. In this study, we aim to detect renal changes in the early phase of AAN with T2 mapping. The results suggest that T2 mapping may be a valuable tool in experimental studies and clinical practice of acute phase of AAN.

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