Abstract #2481

Association between visceral adipose tissue and hepatic steatosis and steatohepatitis in obese patients

Ilkay S Idilman^1,2, Hsien Min Low³, Tolga Gidener¹, Kenneth Philbrick¹, Taofic Mounajjed⁴, Jiahui Li¹, Alina Allen⁵, Meng Yin¹, and Sudhakar K Venkatesh¹

¹Radiology, Mayo Clinic, Rochester, MN, United States, ²Radiology, Hacetep University, Ankara, Turkey, ³Radiology, Tan Tock Seng Hospital, Singapore, Singapore, ⁴Pathology, Mayo Clinic, Rochester, MN, United States, ⁵Gastroenterology and Hepatology, Mayo Clinic, Rochester, MN, United States

In this study we measured visceral adipose tissue (VAT), proton density fat fraction (PDFF) of liver, liver volume and correlated with liver biopsy features in obese patients at risk for non-alcoholic fatty liver disease (NAFLD). VAT shows moderately significant association with PDFF and liver volume. VAT also shows weak but significant correlation with hepatic steatosis, non-alcoholic steatohepatitis (NASH) and fibrosis at histology. Liver volume was significantly larger in patients in hepatic steatosis, NASH and fibrosis. VAT has moderate accuracy for detection of hepatic steatosis (0.71), NASH (0.68), fibrosis (0.68) and significant fibrosis (0.73) at histology.

How to access this content:

For one year after publication, abstracts and videos are only open to registrants of this annual meeting. Registrants should use their existing login information. Non-registrant access can be purchased via the ISMRM E-Library.

After one year, current ISMRM & ISMRT members get free access to both the abstracts and videos. Non-members and non-registrants must purchase access via the ISMRM E-Library.

After two years, the meeting proceedings (abstracts) are opened to the public and require no login information. Videos remain behind password for access by members, registrants and E-Library customers.

Click here for more information on becoming a member.