The aim of this study was to identify Dynamic Gadoxetate-Enhanced MRI (DGE-MRI) biomarkers that can improve predictions of post-hepatectomy liver function. 29 patients requiring resection for colorectal liver metastases were recruited, with post-operative bilirubin as outcome measure. The results suggest that: (a) functional imaging substantially improves outcome predictions over demographical and biochemical tests; (b) it is critical to separately characterise the future liver remnant; (c) volumetry does not offer any added predictive value. We conclude that DGE-MRI may improve patient selection for hepatectomy, potentially reducing the risk of post-hepatectomy liver failure while allowing more patients to be operated.
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