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Abstract #2489

Quantitative Assessment of Liver Function by Using T1mapping based on Gadoxetic Acid–enhanced MRI

Xueqin Zhang1, Jian LU1, Jifeng JIANG1, and Weibo CHEN2
1the Third People’s Hospital of Nantong, Nantong, China, 2Philips Healthcare, Shanghai, China

The purpose of this study was to investigate whether liver function as determined by indocyanine green (ICG) clearance can be estimated quantitatively from magnetic resonance T1mapping with Gd-EOB-DTPA. We used Look-Locker sequences to acquire T1 mapping images pre and post-contrast at 5, 10, 15 and 20 minutes after Gd-EOB-DTPA administration, T1 relaxation times of the liver were measured, reduction rates of T1 relaxation times were calculated, our study showed that Gd-EOB-DTPA-enhanced T1mapping MRI is helpful for the quantitative evaluation of liver function, T1 relaxation time post-contrast at 20 minutes was the independent factor to predict ICG R15>20%.

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