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Abstract #2493

Effect of spatial resolution on Gradient Echo Magnetic Resonance Elastography at 3T

Chris R Bradley1,2, Deirdre McGrath1,2, Eleanor F Cox1,2, and Susan T Francis1,2
1Sir Peter Mansfield Imaging Centre, University of Nottingham, Nottingham, United Kingdom, 2NIHR Nottingham Biomedical Research Centre, Nottingham University Hospitals NHS Trust and University of Nottingham, Nottingham, United Kingdom

Iron-mediated T2* effects are more prominent in MRE data acquired at 3T compared to 1.5 T, and have been suggested to lead to failure rates of up to 15% for MRE at 3T. MRE based liver stiffness was measured using the QIBA recommendation with a 2D gradient‐recalled‐echo MRE sequence using a 1.5x4.5x10 mm3 acqusition. For comparison, MRE data was also collected at 4.5mm isotropic spatial resolution. A larger voxel volume in the MRE acquisition provided higher SNR which in turn resulted in a higher proportion of voxels being fit for stiffness with confidence >0.95.

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