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Abstract #2501

Evaluation of liver fibrosis and cirrhosis on the basis of T1 mapping and the impact of inflammation, age and liver volume as confounding factors

Hanns-Christian Breit1, David Winkel2, and Tobias Heye2
1Radiology, University Hospital of Basel, Basel, Switzerland, 2University Hospital of Basel, Basel, Switzerland

Aim of our study was to evaluate confounding factors for the assessment of liver fibrosis. A total of 200 patients were retrospectively included (67 patients with fibrosis or cirrhosis, 40 patients with acute elevation of laboratory parameters, 93 healthy patients). T1 values were significantly lower in healthy patients without known fibrotic changes than in patients with acute liver disease or known fibrosis or cirrhosis. Therefor T1 mapping seems to be a capable predictor for the detection of liver fibrosis and cirrhosis.

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