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Abstract #2509

Visualization of pancreas and reproducibility of metrics with diffusion kurtosis imaging in rats at 11.7T MRI

Tingting Zhang1, Yimei Lu1, He Wang2, and Dengbin Wang1
1Radiology, Xinhua Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China, 2Institute of Science and Technology for Brain-Inspired Intelligence, Shanghai, China

This study aimed to visualize the pancreas of rats with uncontrast MRI and validate the contour of pancreas by infusing gadolinium solution into the biliopancreatic duct for post-mortem imaging at 11.7 T MRI. Also, the reproducibility of metrics with diffusion kurtosis imaging (DKI) were evaluated in the pancreas of rats. We found that MRI at 11.7T could facilitate preclinical experiments in rodent pancreas and DKI appeared to be a useful noninvasive imaging tool to research pancreatic diseases with satisfactory reproducibility.

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