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Abstract #2508

Acute pancreatic fat change in probiotics and intermittent fasting trial

Jun Lu1, Dech Dokpuang1, Rinki Murphy2, Lindsay Plank2, John Zhiyong Yang1, Reza Nemati3, and Kevin Haokun He4
1School of Science, Auckland University of Technology, Auckland, New Zealand, 2School of Medicine, University of Auckland, Auckland, New Zealand, 3Canterbury Health Laboratories, Canterbury District Health Board, Christchurch, New Zealand, 4Saint Kentigern College, Auckland, New Zealand

Pancreatic fat has been reported to be closely related to type 2 diabetes risk, hence is the subject of our investigation in a clinical trial. Pancreatic fat changes before and after a 12-week intermittent fasting programme with or without daily probiotic were determined using magnetic resonance imaging (MRI). Two-point Dixon protocol was used to scan patients and manual image-processing method was used to quantify the fat. A significant reduction in pancreatic fat was observed after intermittent fasting, while addition of probiotic did not increase pancreatic fat reduction.

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