Abstract #2507

DCE-MRI with a free-breathing compressed sensing VIBE for pancreatic ductal adenocarcinoma: correlation with ECV fraction

Yoshihiko Fukukura¹, Yuichi Kumagae¹, Hiroaki Nagano¹, Koji Takumi¹, Hiroshi Imai², Marcel Dominik Nickel³, and Takashi Yoshiura¹

¹Kagoshima University Graduate School of Medical and Dental Sciences, Kagoshima, Japan, ²Siemens Healthcare K.K., Tokyo, Japan, ³Siemens Healthcare, Erlangen, Germany

This study focused on the feasibility of dynamic contrast-enhanced MRI (DCE-MRI) with compressed sensing T1-weighted volumetric interpolated breath-hold examination (csVIBE) for pancreatic ductal adenocarcinoma (PDAC) and correlation with extracellular volume fraction (ECV). Our results indicated that DCE-MRI obtained with csVIBE is feasible for the assessment of PDACs and the ECV fraction can be used in place of DCE-MRI parameters for predicting treatment response or survival in patients with PDAC.

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