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Abstract #2507

DCE-MRI with a free-breathing compressed sensing VIBE for pancreatic ductal adenocarcinoma: correlation with ECV fraction

Yoshihiko Fukukura1, Yuichi Kumagae1, Hiroaki Nagano1, Koji Takumi1, Hiroshi Imai2, Marcel Dominik Nickel3, and Takashi Yoshiura1
1Kagoshima University Graduate School of Medical and Dental Sciences, Kagoshima, Japan, 2Siemens Healthcare K.K., Tokyo, Japan, 3Siemens Healthcare, Erlangen, Germany

This study focused on the feasibility of dynamic contrast-enhanced MRI (DCE-MRI) with compressed sensing T1-weighted volumetric interpolated breath-hold examination (csVIBE) for pancreatic ductal adenocarcinoma (PDAC) and correlation with extracellular volume fraction (ECV). Our results indicated that DCE-MRI obtained with csVIBE is feasible for the assessment of PDACs and the ECV fraction can be used in place of DCE-MRI parameters for predicting treatment response or survival in patients with PDAC.

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