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Abstract #2506

Histogram Analysis of T1 relaxation time in the rotating frame and Apparent Diffusion Coefficient for Diagnosis of Liver Fibrosis

Jing Li1, Xinming Li1, Xianyue Quan1, Genwen Hu2, Yingjie Mei3, Da Shi1, Shisi Li4, Zhendong Qi1, and Xiao Zhang5
1Zhujiang Hospital, Southern Medical University, Guangzhou, China, 2Shenzhen People’s Hospital, Clinical Medical College of Jinan University, Shenzhen, China, 3Phlips Healthcare, Guangzhou, China, 4The Third Affiliated Hospital of Southern Medical University, Guangzhou, China, 5Guangdong Provincial Key Laboratory of Medical Image Processing, School of Biomedical Engineering, Southern Medical University, Guangzhou, China

To explore the potential of histogram analysis to evaluate the liver fibrosis stages, histogram of T1rho and ADC were acquired from liver fibrosis model built in seventy-five rats by injecting 50% carbon tetrachloride and olive oil. In this study, we found that the parameters of histogram analysis showed strong correlations with liver fibrosis stages, as well as inflammatory activity,while T1rho is regarded to be better than ADC.

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