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Abstract #2513

PANCREATIC IRON IN PATIENTS WITH HEMOCHROMATOSIS: NOT AS RARE AS CARDIAC IRON

Jin Yamamura1, Peter Nielsen2, Sarah Keller3, Regine Grosse4, Björn Schönnagel1, and Roland Fischer2,5
1Diagnostic and Interventional Radiology, University Medical Center Hamburg-Eppendorf, Hamburg, Germany, 2Biochemistry, University Medical Center Hamburg-Eppendorf, Hamburg, Germany, 3Diagnsotic and Interventional Radiology, Universitätsmedizin Charité, Berlin, Germany, 4Hemato-Oncology, University Medical Center Hamburg-Eppendorf, Hamburg, Germany, 5Diagnostic Radiology, UCSF-Benioff Children's Hospital Oakland, Oakland, CA, United States

HFE-associated hereditary Hemochromatosis (HFE-HH) is the most frequent monogenic genetic disorder in the Caucasian population. The excessive iron storage in organs are common, affecting the liver mostly (> 90 %) resulting in a potentially severe liver damage (fibrosis, cirrhosis). In recent years, hepatic and cardiac iron deposition has been studied in detail. Due to its involvement in the development of diabetes - a frequent co-morbidity in iron overload diseases - pancreatic iron should become a field of interest. This study aims to determine the pancreatic iron and fat content in patients with HFE-HH.

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