Abstract #2514

Quantification of pancreatic volume and clinical correlations in patients with hemoglobinopathies

Antonella Meloni¹, Massimiliano Missere², Gennaro Restaino², Laura Pistoia¹, Vincenzo Positano¹, Emanuele Grassedonio³, Nicolò Schicchi⁴, Giuseppe Peritore⁵, Francesco Massei⁶, Nicola Dello Iacono⁷, Angelica Barone⁸, and Alessia Pepe¹

¹MRI Unit, Fondazione G. Monasterio CNR-Regione Toscana, Pisa, Italy, ²Fondazione di Ricerca e Cura "Giovanni Paolo II", Campobasso, Italy, ³Policlinico "Paolo Giaccone", Palermo, Italy, ⁴Azienda Ospedaliero-Universitaria Ospedali Riuniti "Umberto I-Lancisi-Salesi", Ancona, Italy, ⁵"ARNAS" Civico, Di Cristina Benfratelli, Palermo, Italy, ⁶Azienda Ospedaliero Universitaria Pisana – Stabilimento S.Chiara, Pisa, Italy, ⁷Ospedale Casa Sollievo della Sofferenza IRCCSOspedale Casa Sollievo della Sofferenza IRCCS, San Giovanni Rotondo, Italy, ⁸Azienda Ospedaliero-Universitaria di Parma, Parma, Italy

In patients with hemoglobinopathies fat infiltration is a common finding and pancreatic volume is significantly lower than in normal subjects but it is not associated to age or gender. Pancreatic iron overload is present in the 74% of the patients and it is associated with reduced pancreatic volume. Patients with diabetes have a lower pancreatic volume.

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