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Abstract #2519

Why you shouldn’t report pancreas MRI-PDFF ‘for free’ from a liver scan

Alexandre Triay Bagur1, Ged Ridgway2, Michael Brady2, and Daniel Bulte1
1Department of Engineering Science, University of Oxford, Oxford, United Kingdom, 2Perspectum Diagnostics, Oxford, United Kingdom

The proximal locations of the liver and pancreas in the abdomen make it tempting to report the PDFF of both in a single scan. However, published methods for liver fat measurement need revision before they accurately measure pancreatic fat. UK Biobank scans were used to quantify the quality of fits of a method developed previously for liver PDFF when applied to the pancreas. Pancreas fits were an order of magnitude lower than fits in the liver or the spleen. This could be due to a suboptimal acquisition or because the liver fat model does not approximate well to the pancreas.

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