Abstract #2639

Improved Diffusion-Weighted Imaging of Rat Kidney Using Interleaved Multishot EPI with 2D Navigators

Qiang Liu¹, Zhongbiao Xu², Xinyuan Zhang¹, Zhifeng Chen¹, Rongli Zhang³, Yaohui Wang⁴, Kaixuan Zhao¹, Ed X. Wu^5,6, and Yanqiu Feng¹

¹School of Biomedical Engineering, Guangdong Provincial Key Laboratory of Medical Image Processing, Southern Medical University, Guangzhou, China, ²Department of Radiotherapy, Cancer Center, Guangdong Provincial People's Hospital & Guangdong Academy of Medical Science, Guangzhou, China, ³School of Medicine, Guangdong Provincial People's Hospital , South China University of Technology, Guangzhou, China, ⁴Institute of Electrical Engineering, Chinese Academy of Sciences, Beijing, China, ⁵Laboratory of Biomedical Imaging and Signal Processing, The University of Hong Kong, Hong Kong SAR, China, ⁶Department of Electrical and Electronic Engineering, The University of Hong Kong, Hong Kong SAR, China

This work aimed to improve rat kidney diffusion-weighted imaging (DWI) by using interleaved multishot echo planar imaging (EPI) with 2D navigators. The data of shots were combined to reconstruct the final images by using the IRIS processing pipeline. The in vivo rat imaging results show that the multishot EPI approach obtained renal diffusion-weighted images with higher resolution and less geometric distortion, compared single-shot EPI. The DWI of rat kidney can be significantly improved by 2D navigated multishot EPI.

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