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Abstract #2639

Improved Diffusion-Weighted Imaging of Rat Kidney Using Interleaved Multishot EPI with 2D Navigators

Qiang Liu1, Zhongbiao Xu2, Xinyuan Zhang1, Zhifeng Chen1, Rongli Zhang3, Yaohui Wang4, Kaixuan Zhao1, Ed X. Wu5,6, and Yanqiu Feng1
1School of Biomedical Engineering, Guangdong Provincial Key Laboratory of Medical Image Processing, Southern Medical University, Guangzhou, China, 2Department of Radiotherapy, Cancer Center, Guangdong Provincial People's Hospital & Guangdong Academy of Medical Science, Guangzhou, China, 3School of Medicine, Guangdong Provincial People's Hospital , South China University of Technology, Guangzhou, China, 4Institute of Electrical Engineering, Chinese Academy of Sciences, Beijing, China, 5Laboratory of Biomedical Imaging and Signal Processing, The University of Hong Kong, Hong Kong SAR, China, 6Department of Electrical and Electronic Engineering, The University of Hong Kong, Hong Kong SAR, China

This work aimed to improve rat kidney diffusion-weighted imaging (DWI) by using interleaved multishot echo planar imaging (EPI) with 2D navigators. The data of shots were combined to reconstruct the final images by using the IRIS processing pipeline. The in vivo rat imaging results show that the multishot EPI approach obtained renal diffusion-weighted images with higher resolution and less geometric distortion, compared single-shot EPI. The DWI of rat kidney can be significantly improved by 2D navigated multishot EPI.

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