Abstract #2640

Second-order Motion Compensated Intravoxel Incoherent Motion Analysis of the Kidney

Yuki Koshino¹, Naoki Ohno², Tosiaki Miyati², Tetsuo Ogino³, Yu Ueda³, Naoki Hori¹, Yukihiro Matsuura¹, Toshifumi Gabata⁴, and Satoshi Kobayashi^1,2,4

¹Radiology Division, Kanazawa University Hospital, Ishikawa, Japan, ²Faculty of Health Sciences, Institute of Medical, Pharmaceutical and Health Sciences, Kanazawa University, Ishikawa, Japan, ³Philips Japan, Tokyo, Japan, ⁴Department of Radiology, Kanazawa University Graduate School of Medical Sciences, Ishikawa, Japan

To investigate the potential benefit of second-order motion compensated (2^nd-MC) diffusion encoding scheme on intravoxel incoherent motion (IVIM) analysis of the kidney, we compared the IVIM diffusion parameters and repeatability between the 2^nd-MC and conventional diffusion gradients. Our results showed that the 2^nd-MC diffusion gradients show better fitting accuracy and repeatability of IVIM diffusion parameters of the kidney compared with the conventional diffusion gradients. Therefore, the 2^nd-MC diffusion encoding scheme could enable us to reduce the bulk motion effect mainly caused by cardiac and respiratory motion during diffusion sensitization.

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