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Abstract #2640

Second-order Motion Compensated Intravoxel Incoherent Motion Analysis of the Kidney

Yuki Koshino1, Naoki Ohno2, Tosiaki Miyati2, Tetsuo Ogino3, Yu Ueda3, Naoki Hori1, Yukihiro Matsuura1, Toshifumi Gabata4, and Satoshi Kobayashi1,2,4
1Radiology Division, Kanazawa University Hospital, Ishikawa, Japan, 2Faculty of Health Sciences, Institute of Medical, Pharmaceutical and Health Sciences, Kanazawa University, Ishikawa, Japan, 3Philips Japan, Tokyo, Japan, 4Department of Radiology, Kanazawa University Graduate School of Medical Sciences, Ishikawa, Japan

To investigate the potential benefit of second-order motion compensated (2nd-MC) diffusion encoding scheme on intravoxel incoherent motion (IVIM) analysis of the kidney, we compared the IVIM diffusion parameters and repeatability between the 2nd-MC and conventional diffusion gradients. Our results showed that the 2nd-MC diffusion gradients show better fitting accuracy and repeatability of IVIM diffusion parameters of the kidney compared with the conventional diffusion gradients. Therefore, the 2nd-MC diffusion encoding scheme could enable us to reduce the bulk motion effect mainly caused by cardiac and respiratory motion during diffusion sensitization.

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