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Abstract #2641

Reliability of Water-Lipid Separation in the Kidney Measured by Accelerated In Vivo Magnetic Resonance Spectroscopic Imaging at 3 T

Ahmad Alhulail1,2, Mahsa Servati1,3, Nathan Ooms1,3, Oguz Akin4, Alp Dincer5,6, M. Albert Thomas7, Ulrike Dydak1,3, and Uzay E Emir1,8
1School of Health Sciences, Purdue University, West Lafayette, IN, United States, 2Department of Radiology and Medical Imaging, Prince Sattam bin Abdulaziz University, Al Kharj, Saudi Arabia, 3Department of Radiology and Imaging Sciences, Indiana University School of Medicine, Indianapolis, IN, United States, 4Department of Radiology, Memorial Sloan Kettering Cancer Center, New York, NY, United States, 5Department of Radiology, School of Medicine, Acıbadem Mehmet Ali Aydinlar University, Istanbul, Turkey, 6Center for Neuroradiological Applications and Research, Acıbadem Mehmet Ali Aydinlar University, Istanbul, Turkey, 7Department of Radiology, University of California Los Angeles, Los Angeles, Los Angeles, CA, United States, 8Weldon School of Biomedical Engineering, Purdue University, West Lafayette, IN, United States

MRS could be useful for characterization of the renal cell carcinoma by detecting lipid content. However, single-voxel MRS cannot show the distribution of lipids for heterogeneous tumors. We propose a fast MRSI sequence to map the distribution of lipid metabolites within a clinically acceptable time frame at 3T. The proposed MRSI technique provided high-quality data with reproducible quantitative outputs. The coefficient of variance for the quantified fat fraction was less than 1%.

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