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Abstract #2675

Short-term repeatability of magnetic resonance fingerprinting for T1 and T2 measurements of metastatic bone lesions in prostate cancer patients

Matthew R Orton1, Mihaela Rata2, Nina Tunariu2, Andra Curcean2, Julie Hughes2, Erica Scurr2, James D'arcy1, Matthew D Blackledge1, and Dow-Mu Koh2
1Division of Radiotherapy and Imaging, Institute of Cancer Research, Sutton, United Kingdom, 2Department of Radiology, Royal Marsden NHS Foundation Trust, Sutton, United Kingdom

Accurate characterisation of bone metastases and their response to treatment remains an unmet need in oncology. Magnetic resonance fingerprinting (MRF) is an imaging technique that yields inherently co-registered quantitative images from a single acquisition, so this work aims to evaluate measurement repeatability of MRF when measuring T1 and T2 relaxation times in metastatic bone disease. We found good measurement repeatability of 6% for lesion mean T1 and 23% for lesion mean T2.

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