Dynamic phosphorus magnetic resonance spectroscopy (31P-MRS) is a method used for in vivo studies of skeletal muscle function including measurements of phosphocreatine (PCr) synthesis rate during recovery from submaximal exercise. However, the molecular events underlying the PCr resynthesis rate are still under debate. Therefore, our goal was to assess the PCr resynthesis rate from 31P-MRS spectra collected from the skeletal muscle (vastus lateralis) of healthy adults and investigate associations between PCr resynthesis and levels of mitochondria-related transcripts and proteins in the same muscle (NAMPT, NQO1, PGC-1α, and SIRT1).
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