Abstract #2734

MP2RAGE improves robustness of 3D T1-Mapping of Hip Cartilage compared to Conventional Dual-Flip-Angle Acquisition

Bernd A Jung¹, Onur Afacan², Till Lerch¹, Young-Jo Kim³, Tobias Kober^4,5,6, Michael Ith¹, Markus Klarhoefer⁷, and Florian Schmaranzer¹

¹Diagnostic, Interventional and Pediatric Radiology, University Hospital Bern, Bern, Switzerland, ²Dept of Radiology, Boston Children`s Hospital, Boston, MA, United States, ³Dept of Orthopaedic Surgery, Boston Children`s Hospital, Boston, MA, United States, ⁴Advanced Clinical Imaging Technology, Siemens Healthcare, Lausanne, Switzerland, ⁵Dept of Radiology, Lausanne University Hospital and University of Lausanne, Lausanne, Switzerland, ⁶LTS5, École Polytechnique Fédérale de Lausanne (EPFL), Lausanne, Switzerland, ⁷Siemens Healthcare, Zuerich, Switzerland

Although commonly used for T1 mapping of hip cartilage, 3D dual flip angle (DFA) techniques are sensitive to flip angle variations related to B1 inhomogeneities. Therefore, the IR-based MP2RAGE technique was compared with a standard 3D DFA acquisition including B1 field mapping for T1 mapping of hip cartilage in a phantom study and in healthy volunteers at 3T. For the phantom study, a 2D IR-based sequence was additionally acquired to provide reference T1 maps. MP2RAGE resulted in more accurate T1 values with less regional variations compared to DFA method and therefore enables a more robust T1 mapping of hip cartilage.

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