Abstract #2752

Prospective clinical validation of 3D MP2RAGE for T1 mapping of hip cartilage: Preliminary results in patients with hip pain

Florian Schmaranzer^1,2, Eduardo Novais², Young-Jo Kim², Tobias Kober^3,4,5, Bernd Jung¹, Sarah Bixby⁶, and Onur Afacan⁶

¹Department of Diagnostic, Interventional and Pediatric Radiology, University of Bern, Inselspital Bern, Bern, Switzerland, ²Department of Orthopaedic Surgery, Harvard Medical School, Boston Children`s Hospital, Boston, MA, United States, ³Advanced Clinical Imaging Technology, Siemens Healthcare, Lausanne, Switzerland, ⁴Department of Radiology, Lausanne University Hospital and University of Lausanne, Lausanne, Switzerland, ⁵École Polytechnique Fédérale de Lausanne (EPFL), Lausanne, Switzerland, ⁶Department of Radiology, Harvard Medical School, Boston Children`s Hospital, Boston, MA, United States

Current standard techniques for T1 mapping of hip cartilage are affected by flip angle variations due to B1-field inhomogeneities at 3T. The aim was to prospectively compare a 3D MP2RAGE for T1 mapping of cartilage to a 2D-IR based reference standard in the patients with hip pain undergoing indirect MR arthrography. 3D MP2RAGE correlated well with the 2D-IR reference standard and showed a minor systematic bias. This supports the continued use of 3D MP2RAGE in patients undergoing joint preserving hip surgery with the goal to establish prognostic predictors to predict the success or failure of these interventions.

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